For heteronuclear 2D experiments, a combiner was used to connect the transmitter and decoupler outputs to the single coax cable connected to the BBC set-up. Appropriate high pass or band filters were used in the high-gamma, respectively, low-gamma channels.
Structural description of the Na3AlF6-Na2B4O7-TiO2 system. Part II: A multinuclear approach
Details on acquisition parameters are provided in the Supplementary Table 1. The chip was placed inside a standardized Fluidic Slide that fits into a custom-built aluminium Fluidic Connect chip holder with a diameter of 3. The chip holder consists of two halves assembled together using brass screws. The front half of the holder was functionalized with microfluidic access holes enabling leak-free connections, while electrical connections to the copper electrodes were accessible from the other half of the holder.
The two coils can be addressed contemporaneously or separately, for fast reactions monitoring or for homonuclear or heteronuclear applications, and one of the possibilities is to use one of the coils for a field-lock circuit. The experiments we describe here have been performed using the top coil only. The multiple microfluidic inlets allow for on-chip mixing of reactants or cooling through a separate microfluidic channel. Standard microfluidic connections and plug-and-play electrical connections were purchased from Micronit Microfluidics BV.
NMR experiments were carried out using an Oxford Instruments 9. All experiments were acquired in non-locked mode, adjusting shims on the free induction decay. Standard pulse sequences from VnmrJ 2. Arrayed experiments were processed with VnmrJ software; the other data were processed using MestReNova 6. The acquisition parameters for the heteronuclear 2D experiments described in this article are summarized in the Supplementary Table 1.
The obtained values were of 3, for the BBC microprobe and 3, for the 1 H-tuned microprobe. For mass-limited samples, the mass molar sensitivity, S m , is a better figure of merit for comparison of probes with different volumes 8 , and is defined as. Considering the lower magnetic field used in this work 9. An example of an equivalent-circuit simulation Supplementary Fig. How to cite this article: Fratila, R. Multinuclear nanoliter one-dimensional and two-dimensional NMR spectroscopy with a single non-resonant microcoil.
Solid-state nuclear magnetic resonance - Wikipedia
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